ELMO1 Rabbit monoclonal antibody

Size

POA

SKU:: A5169
Additional Names:: CED-12|CED12|ELMO-1|ELMO1
Application:: ELISA, WB, IHC-P
Molecular Weight:: 84kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: KGALKQNKEVLELAFSILYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN
Uniprot:: Q92556
Synonyms:: CED-12;ced-12 homolog 1;CED12;ELMO-1;engulfment and cell motility protein 1;Protein ced-12 homolog
Extra Details:: This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants.