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  2. Monoclonal

A4737

PDK2 Rabbit monoclonal antibody

Size

POA

SKU:
A4737
Additional Names:
PDHK2|PDK2|PDKII
Application:
ELISA, WB, IHC-P
Molecular Weight:
46kda
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
YSTAPTPQPGTGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS
Uniprot:
Q15119
Synonyms:
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial;PDH kinase 2;PDHK2;PDKII;Pyruvate dehydrogenase kinase isoform 2;pyruvate dehydrogenase kinase, isoenzyme 2;pyruvate dehydrogenase kinase, isozyme 2;pyruvate dehydrogenase, lipoamide, kinase isozyme 2, mitochondrial
Extra Details:
This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Shipping Conditions:
Blue Ice