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  2. Monoclonal

A4532

Coagulation Protein C Rabbit monoclonal antibody

Size

POA

SKU:
A4532
Additional Names:
APC|Coagulation Protein C|PC|PROC1|THPH3|THPH4
Application:
ELISA, WB, IF
Molecular Weight:
52kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
IALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHIRDKEAPQKSWAP
Uniprot:
P04070
Synonyms:
activated protein C;anticoagulant protein C;APC;autoprothrombin IIA;blood coagulation factor XIV;PC;prepro-protein C;PROC1;Protein C-Nagoya;THPH3;THPH4;type I protein C;vitamin K-dependent protein C
Extra Details:
This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.
Shipping Conditions:
Blue Ice