CCR8 Rabbit monoclonal antibody

Size

POA

SKU:: A4288
Additional Names:: CC-CKR-8|CCR-8|CCR8|CDw198|CKRL1|CMKBR8|CMKBRL2|CY6|GPRCY6|TER1
Application:: ELISA, WB, IF, ICC
Molecular Weight:: 41kda
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: FWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL
Uniprot:: P51685
Synonyms:: C-C chemokine receptor type 8;CC chemokine receptor 8;CC chemokine receptor CHEMR1;CC-chemokine receptor chemr1;CC-CKR-8;CCR-8;CDw198;chemokine (C-C motif) receptor 8;chemokine (C-C) receptor 8;chemokine (C-C) receptor-like 2;chemokine receptor-like 1;CKRL1;CMKBR8;CMKBRL2;CY6;GPR-CY6;GPRCY6;TER1
Extra Details:: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.

Shipping Conditions:: Blue Ice