Calbindin Rabbit monoclonal antibody

Size

POA

SKU:: A4284
Additional Names:: CALB|Calbindin|D-28K
Application:: ELISA, WB, IF
Molecular Weight:: 30 kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MAESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSC
Uniprot:: P05937
Synonyms:: CALB;calbindin;calbindin 1, (28kD);calbindin 1, 28kDa;calbindin 27;calbindin D28;D-28K;RTVL-H protein;vitamin D-dependent calcium-binding protein, avian-type
Extra Details:: The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease.