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A4064

SMMHC/MYH11 Rabbit monoclonal antibody

Size

POA

SKU:
A4064
Additional Names:
AAT4|FAA4|SMHC|SMMHC|SMMHC/MYH11|SMMS-1|VSCM2
Application:
ELISA, WB, IHC-P, IF
Molecular Weight:
227 kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL
Uniprot:
P35749
Synonyms:
AAT4;epididymis secretory sperm binding protein;FAA4;Myosin heavy chain 11;Myosin heavy chain, smooth muscle isoform;myosin-11;myosin, heavy chain 11, smooth muscle;myosin, heavy polypeptide 11, smooth muscle;SMHC;SMMHC;VSCM2
Extra Details:
The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. A chromosomal rearrangement involving this gene is associated with acute myeloid leukemia of the M4Eo subtype. Mutations in this gene are associated with visceral myopathy, megacystis-microcolon-intestinal hypoperistalsis syndrome 2, and familial thoracic aortic aneurysm 4.
Shipping Conditions:
Blue Ice