PDK2 Rabbit polyclonal antibody

Size

£152.00

SKU:: A4012
Additional Names:: PDHK2|PDK2|PDKII
Application:: ELISA, WB, IF, ICC
Molecular Weight:: 46kda
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: PTMAQGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGSTNPAHPKHIGSIDPNCNVSEVVKDAYDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVYVPSHLYHMLFELFKNAMRATVESHESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQPGTGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS
Uniprot:: Q15119
Synonyms:: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial;PDH kinase 2;PDHK2;PDKII;Pyruvate dehydrogenase kinase isoform 2;pyruvate dehydrogenase kinase, isoenzyme 2;pyruvate dehydrogenase kinase, isozyme 2;pyruvate dehydrogenase, lipoamide, kinase isozyme 2, mitochondrial
Extra Details:: This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.