ATP6V1B2 Rabbit polyclonal antibody

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£152.00

SKU:: A3754
Additional Names:: ATP6B1B2|ATP6B2|ATP6V1B2|DOOD|HO57|VATB|Vma2|VPP3|ZLS2
Application:: ELISA, WB
Molecular Weight:: 57kda
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: NLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFERNFIAQGPYENRTVFETLDIGWQLLRIFPKEMLKRIPQSTLSEFYPRDSAKH
Uniprot:: P21281
Synonyms:: ATP6B1B2;ATP6B2;ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2;DOOD;endomembrane proton pump 58 kDa subunit;H+ transporting two-sector ATPase;HO57;testicular secretory protein Li 65;V-ATPase B2 subunit;V-ATPase subunit B 2;V-type proton ATPase subunit B, brain isoform;vacuolar H+-ATPase 56,000 subunit;vacuolar proton pump subunit B 2;VATB;Vma2;VPP3;ZLS2
Extra Details:: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.

Shipping Conditions:: Blue Ice