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A3740

ARHGDIB Rabbit polyclonal antibody

Size

£152.00

SKU:
A3740
Additional Names:
ARHGDIB|D4|GDIA2|GDID4|Ly-GDI|LYGDI|RAP1GN1|RhoGDI2
Application:
ELISA, WB, IHC-P
Molecular Weight:
23 kda
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGDGPVVTDPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLSWEWNLSIKKEWTE
Uniprot:
P52566
Synonyms:
D4;GDIA2;GDID4;Ly-GDI;LYGDI;RAP1GN1;Rho GDI 2;Rho GDP dissociation inhibitor (GDI) beta;rho GDP-dissociation inhibitor 2;rho-GDI beta;RhoGDI2
Extra Details:
Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).
Shipping Conditions:
Blue Ice