A3696
LIS1 Rabbit monoclonal antibody
Size
POA
- SKU:
- A3696
- Additional Names:
- LIS1|LIS2|MDCR|MDS|NudF|PAFAH
- Application:
- ELISA, WB, IF, ICC, IP
- Molecular Weight:
- 47kda
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDVNEELDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPE
- Uniprot:
- P43034
- Synonyms:
- LIS1;LIS2;lissencephaly 1 protein;Lissencephaly-1 protein;MDCR;MDS;NudF;PAF acetylhydrolase 45 kDa subunit;PAF-AH alpha;PAFAH;platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa);platelet-activating factor acetylhydrolase IB subunit beta
- Extra Details:
- This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum.
- Shipping Conditions:
- Blue Ice