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A3605

GUCY2D Rabbit polyclonal antibody

Size

£152.00

SKU:
A3605
Additional Names:
CACD|CACD1|CG-E|CORD5|CORD6|CSNB1I|CYGD|GUC1A4|GUC2D|GUCY2D|LCA|LCA1|RCD2|retGC|RETGC-1|ROS-GC1|ROSGC
Application:
ELISA, WB
Molecular Weight:
95kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
AVFTVGVLGPWACDPIFSRARPDLAARLAAARLNRDPGLAGGPRFEVALLPEPCRTPGSLGAVSSALARVSGLVGPVNPAACRPAELLAEEAGIALVPWGCPWTQAEGTTAPAVTPAADALYALLRAFGWARVALVTAPQDLWVEAGRSLSTALRARGLPVASVTSMEPLDLSGAREALRKVRDGPRVTAVIMVMHSVLLGGEEQRYLLEAAEELGLTDGSLVFLPFDTIHYALSPGPEALAALANSSQLRRAHDAVLTLTRHCPSEGSVLDSLRRAQERRELPSDLNLQQVSPLFGTI
Uniprot:
Q02846
Synonyms:
CACD1;CG-E;cone rod dystrophy 6;CORD5;CORD6;CSNB1I;CYGD;guanylate cyclase 2D, membrane (retina-specific);Guanylate cyclase 2D, retinal;GUC1A4;GUC2D;LCA;LCA1;RCD2;retGC;RETGC-1;retinal guanylate cyclase 1;retinal guanylyl cyclase 1;rod outer segment membrane guanylate cyclase;ROS-GC;ROS-GC1;ROSGC
Extra Details:
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.
Shipping Conditions:
Blue Ice