[KO Validated] EIF2AK1 Rabbit polyclonal antibody

Size

POA

SKU:: A3415
Additional Names:: HCR|hHRI|HRI|K1|LEMSPAD
Application:: ELISA, WB
Molecular Weight:: 74kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: QTEAQYHLMLHIQMQLCELSLWDWIVERNKRGREYVDESACPYVMANVATKIFQELVEGVFYIHNMGIVHRDLKPRNIFLHGPDQQVKIGDFGLACTDILQKNTDWTNRNGKRTPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVVLLELFQPFGTEMERAEVLTGLRTGQLPESLRKRCPVQAKYIQHLTRRNSSQRPSAIQLLQSELFQNSGNVNLTLQMKIIEQEKEIAELKKQLNLLSQDKGVRDDGKDGGVG
Uniprot:: Q9BQI3
Synonyms:: eukaryotic translation initiation factor 2-alpha kinase 1;HCR;heme regulated initiation factor 2 alpha kinase;heme sensitive initiation factor 2a kinase;heme-controlled repressor;heme-regulated eukaryotic initiation factor eIF-2-alpha kinase;heme-regulated inhibitor;heme-regulated repressor;hemin-sensitive initiation factor 2-alpha kinase;hHRI;HRI;LEMSPAD
Extra Details:: The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.