Rabbit anti-Human CD192/CCR2 monoclonal antibody

Size

POA

SKU:: A28977
Additional Names:: CC-CKR-2|CCR-2|CCR2A|CCR2B|CD192|CKR2|CKR2A|CKR2B|CMKBR2|MCP-1-R
Application:: Flow Cytometry
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Uniprot:: P41597
Synonyms:: C-C chemokine receptor type 2;CC-CKR-2;CCR-2;CCR2A;CCR2B;CD192;chemokine (C-C motif) receptor 2;CKR2;CKR2A;CKR2B;CMKBR2;MCP-1 receptor;MCP-1-R;monocyte chemoattractant protein 1 receptor;monocyte chemotactic protein 1 receptor
Extra Details:: The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3.