A28948
Collagen III alpha 1/COL3A1 Rabbit monoclonal antibody
Size
POA
- SKU:
- A28948
- Additional Names:
- Col3a-1|Tsk-2|Tsk2
- Application:
- ELISA, IHC-P, IF
- Species Reactivity:
- Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Uniprot:
- P08121
- Synonyms:
- alpha-1 type III collagen;alpha1 (III) collagen;AW550625;Col3;Col3a-1;collagen alpha-1(III) chain;collagen, fetal;collagen, type III, alpha 1;EDS4A;EDSVASC;Ehlers-Danlos syndrome type IV, autosomal dominant;PMGEDSV;procollagen, type III, alpha 1;Tsk;Tsk-;Tsk-2;Tsk2
- Extra Details:
- This gene encodes the alpha-1 subunit of the fibril-forming type III collagen found in bone, cartilage, dentin, tendon, bone marrow stroma and other connective tissue. The encoded protein forms homotrimeric type III procollagen that undergoes proteolytic processing during fibril formation. A majority of mice lacking the encoded protein die within two days of birth but about 5% of the animals survive to adulthood. The surviving mice exhibit severe cortical malformation and experience significantly shorter lifespan. The mutant mouse named "tight skin 2" exhibiting systemic sclerosis phenotype was found to harbor a missense point mutation in this gene. A pseudogene of this gene has been defined on chromosome 8.
- Shipping Conditions:
- Blue Ice