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  2. Monoclonal

A28903

PSD95 Rabbit monoclonal antibody

Size

POA

SKU:
A28903
Additional Names:
Dlgh4|PSD-95|PSD95|SAP90|SAP90A
Application:
ELISA, WB, IHC-P, IF
Molecular Weight:
95 kDa/75 kDa
Species Reactivity:
Mouse
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
This information is considered to be commercially sensitive.
Formulation:
Unmodified
Uniprot:
Q62108
Synonyms:
discs large homolog 4;discs, large homolog 4;disks large homolog 4;Dlgh;Dlgh4;MRD62;post-synaptic density protein 95;postsynaptic density protein 95;PSD;PSD-;PSD-95;PSD-95 alpha 2b;PSD-95 beta;PSD95;SA;SAP-90;SAP90;SAP90A;synapse-associated protein 90;Tax interaction protein 15
Extra Details:
Enables ionotropic glutamate receptor binding activity and scaffold protein binding activity. Involved in several processes, including dendritic spine morphogenesis; locomotory exploration behavior; and neurotransmitter receptor localization to postsynaptic specialization membrane. Acts upstream of or within protein localization to synapse; regulation of long-term neuronal synaptic plasticity; and synaptic vesicle maturation. Located in several cellular components, including axon; postsynaptic density; and synaptic vesicle. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse. Colocalizes with postsynaptic membrane. Is expressed in central nervous system; dorsal root ganglion; and sensory organ. Used to study Williams-Beuren syndrome and autism spectrum disorder. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 62. Orthologous to human DLG4 (discs large MAGUK scaffold protein 4).
Shipping Conditions:
Blue Ice