APC Rabbit anti-Rat CD161 monoclonal antibody

Size

POA

SKU:: A28881
Additional Names:: NKR-P1A|Nkrp1a
Application:: Flow Cytometry
Species Reactivity:: Rat
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Species:: Rat
Uniprot:: P27471
Synonyms:: antigen 3.2.3;C-type lectin domain family 5 member B;CD161;CD161 antigen-like family member A;CLEC5B;hNKR-P1A;killer cell lectin-like receptor subfamily B member 1;killer cell lectin-like receptor subfamily B member 1A;killer cell lectin-like receptor subfamily B, member 1;natural killer cell surface protein P1-3.2.3;natural killer cell surface protein P1A;NKR;NKR-P1;NKR-P1 3.2.3;NKR-P1A;NKRP1A
Extra Details:: CD161 is a 30 kDa type II transmembrane C-type lectin that is expressed as a homodimer. The NKR-P1 receptor in rats is mainly expressed on NK cells, T cell subsets, dendritic cells and activated monocytes. There are three different types of NKR-P in rats, namely NKR-P1a, NKR-P1b and NKR-P1c. NKR-P1a does not contain an ITIM structure and is an activating receptor, while NKR-P1b contains an ITIM and has an inhibitory function. LLT-1 (ligand lectin like transcript 1) is the ligand, while KLR (killer cell lectin like) acts as the receptor.