TXNIP Rabbit monoclonal antibody

Size

POA

SKU:: A28868
Additional Names:: ARRDC6|EST01027|HHCPA78|THIF|TXNIP|VDUP1
Application:: ELISA, WB, IP
Molecular Weight:: 55 kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Uniprot:: Q9H3M7
Synonyms:: ARRDC6;EST01027;HHCPA78;THIF;thioredoxin binding protein 2;Thioredoxin-binding protein 2;thioredoxin-interacting protein;upregulated by 1,25-dihydroxyvitamin D-3;VDUP1;vitamin D3 up-regulated protein 1
Extra Details:: This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.