A28847
cGAS Rabbit monoclonal antibody
Size
POA
- SKU:
- A28847
- Additional Names:
- E330016A19Rik|Mb21d1
- Application:
- ELISA, WB, IHC-P
- Molecular Weight:
- 62 kDa
- Species Reactivity:
- Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Mouse
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Uniprot:
- Q8C6L5
- Synonyms:
- 2'3'-cGAMP synthase;C6orf150;cGAMP synthase;cyclic GMP-AMP synthase;E330016A19Rik;h-cGAS;Mab-21 domain containing 1;mab-21 domain-containing protein 1;MB21D1;protein MB21D1
- Extra Details:
- The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice