APC Rabbit anti-Monkey/Human CD159a monoclonal antibody

Size

POA

SKU:: A28836
Additional Names:: nkg2A
Application:: Flow Cytometry
Species Reactivity:: Non-human Primate
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Species:: Non-human Primate
Synonyms:: C-lectin type II protein;CD159 antigen-like family member A;CD159A;killer cell lectin like receptor C1;killer cell lectin-like receptor subfamily C, member 1;KLRC1;natural killer cell lectin;natural killer group protein 2;NK cell receptor A;NKG2;NKG2-1/B activating NK receptor;NKG2-A/B type II integral membrane protein;NKG2-A/B-activating NK receptor;NKG2-A/NKG2-B type II integral membrane protein;NKG2-C type II integral membrane protein;NKG2A;uncharacterized protein LOC102121106
Extra Details:: CD159a (also known as NKG2A, encoded by the KLRC1 gene) is an inhibitory receptor on the surface of natural killer (NK) cells and some T cells. After binding to HLA-E molecules, it transmits inhibitory signals to regulate the activity of immune cells. Some viruses (such as HIV and CMV) upregulate the expression of HLA-E to bind to CD159a and inhibit the function of NK cells. Blocking the NKG2A/HLA-E pathway can restore antiviral immunity.