FITC Rabbit anti-Human CD269/BCMA monoclonal antibody

Size

POA

SKU:: A28803
Additional Names:: BCM|BCMA|CD269|TNFRSF13A
Application:: Flow Cytometry
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Uniprot:: Q02223
Synonyms:: B cell maturation antigen;B-cell maturation factor;B-cell maturation protein;BCM;BCMA;CD269;TNFRSF13A;tumor necrosis factor receptor superfamily member 17
Extra Details:: B-cell maturation antigen (BCMA/TNFRSF17/CD269) is a transmembrane glycoprotein and a member of the TNFR superfamily. BCMA expression is mainly restricted to B-cell lineages. The activation signal transduction through this receptor regulates B-cell maturation and plasma cell differentiation upon binding to its ligands (BAFF and APRIL), thus playing a key role in humoral immunity. BCMA is expressed in many B-cell malignancies, and it is selectively expressed on the cell surface of malignant plasma cells with elevated expression. Therefore, BCMA has attracted much attention as a new therapeutic target for the treatment of multiple myeloma.