APC Rabbit anti-Human HLA-B (MITD Specific) monoclonal antibody

Size

POA

SKU:: A28686
Additional Names:: AS|B-4901|HLAB
Application:: Flow Cytometry
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Uniprot:: P01889
Synonyms:: AS;B-4901;HLA class I antigen HLA-B;HLA class I histocompatibility antigen, B alpha chain;HLAB;Human leukocyte antigen B;leukocyte antigen class I-B;major histocompatibility complex, class I, B;MHC class 1 antigen;MHC class I antigen B*7;MHC class I antigen HLA-B alpha chain;MHC class I antigen HLA-B heavy chain;MHC class I antigen SHCHA;MHC class I molecule;MHC HLA-B cell surface glycoprotein;MHC HLA-B transmembrane glycoprotein
Extra Details:: The human leukocyte antigen (HLA) system is a gene complex encoding the major histocompatibility complex (MHC) proteins in humans. These cell-surface proteins are responsible for the regulation of antigen-specific immune responses in humans. HLA genes are highly polymorphic, which enables them to fine-tune the adaptive immune response. The class I HLA molecules (HLA-A, -B, and -C) present small peptide antigens, approximately 8 to 10 amino acids in length, originating from inside the cell to CD8+ cytotoxic T lymphocytes, thereby activating a cytotoxic T-cell response. The class II HLA molecules (HLA-DP, -DM, -DO, -DQ, and -DR) present antigens derived from outside the cell, approximately 15 to 24 residues in length, to CD4+ helper T cells. These helper T cells subsequently secrete cytokines and stimulate B cells to produce antibodies specific to that antigen. The class III HLA region encodes components of the complement system.

Shipping Conditions:: Blue Ice