PE Rabbit anti-Mouse F4/80 monoclonal antibody

Size

POA

SKU:: A28681
Additional Names:: DD7A5-7|EGF-TM7|Emr1|F4/80|Gpf480|Ly71|TM7LN3
Application:: Flow Cytometry
Species Reactivity:: Mouse
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Uniprot:: Q61549
Synonyms:: adhesion G protein-coupled receptor E1;cell surface glycoprotein F4/80;DD7A5-;DD7A5-7;egf-like module containing, mucin-like, hormone receptor-like 1;egf-like module containing, mucin-like, hormone receptor-like sequence 1;EGF-like module receptor 1;EGF-like module-containing mucin-like hormone receptor-like 1;EGF-TM7;Emr;EMR1;EMR1 hormone receptor;F4/80;Gpf480;Ly7;Ly71;TM7L;TM7LN3
Extra Details:: F4/80, also known as EMR1 or Ly71, is a 160 kDa glycoprotein belonging to the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. It is widely used as a murine macrophage marker. F4/80 is expressed on most tissue macrophages, including those in the lung, intestine, peritoneal cavity, thymus, and splenic red pulp, as well as Kupffer cells, Langerhans cells, microglia, and certain dendritic cell subsets. It is notably absent on macrophages residing in the T-cell areas of the spleen, lymph nodes, and Peyer's patches. Although the biological ligand for F4/80 has not yet been identified, this molecule has been reported to be required for the induction of CD8 T cell-mediated peripheral tolerance.

Shipping Conditions:: Blue Ice