[KO Validated] LAMP2 Rabbit monoclonal antibody

Size

POA

SKU:: A28664
Additional Names:: CD107b|Lamp II|Lamp-2|Lamp-2a|Lamp-2b|Lamp-2c|LGP-B|Mac3
Application:: ELISA, Flow Cytometry, WB, IHC-P, IF, ICC, IP
Molecular Weight:: 100-130 kDa
Species Reactivity:: Mouse
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Uniprot:: P17047
Synonyms:: CD107 antigen-like family member B;CD107b;DND;Lam;Lamp;Lamp II;LAMP-2;Lamp-2a;Lamp-2b;Lamp-2c;LAMPB;LGP-96;LGP-B;LGP110;lysosomal membrane glycoprotein 2;lysosomal membrane glycoprotein type B;lysosome-associated membrane glycoprotein 2;Mac;Mac3
Extra Details:: Enables protein domain specific binding activity. Involved in several processes, including autophagosome maturation; protein stabilization; and protein targeting to lysosome involved in chaperone-mediated autophagy. Acts upstream of or within muscle cell cellular homeostasis. Located in bounding membrane of organelle. Is active in lysosome. Is expressed in several structures, including central nervous system; egg cylinder; heart valve; oocyte; and sensory organ. Used to study Danon disease. Human ortholog(s) of this gene implicated in Danon disease and hypertrophic cardiomyopathy. Orthologous to human LAMP2 (lysosomal associated membrane protein 2).