APC Mouse anti-Human CD193/CCR3 monoclonal antibody

Size

POA

SKU:: A28630
Additional Names:: C C CKR3|CC-CKR-3|CD193|CKR 3|CKR3|CMKBR3
Application:: Flow Cytometry
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Mouse
Reactivities:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Uniprot:: P51677
Synonyms:: b-chemokine receptor;C C CKR3;C-C chemokine receptor type 3;C-C CKR-3;CC chemokine receptor 3;CC-CKR-3;CCR-3;CD193;chemokine (C-C motif) receptor 3;CKR 3;CKR3;CMKBR3;eosinophil CC chemokine receptor 3;eosinophil eotaxin receptor
Extra Details:: The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.

Shipping Conditions:: Blue Ice