[KO Validated] GSDME (Full Length+N terminal) Rabbit monoclonal antibody

Size

POA

SKU:: A28582
Additional Names:: 2310037D07Rik|4932441K13Rik|Dfna5|Dfna5h|EG14210|Fin15
Application:: ELISA, WB, IP
Molecular Weight:: 57 kDa(Full length)/35 kDa(N terminal)
Species Reactivity:: Mouse
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Mouse
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Uniprot:: Q9Z2D3
Synonyms:: 2310037D07Rik;4932441K13Rik;deafness associated tumor suppressor;deafness, autosomal dominant 5 homolog;Dfn;Dfna;DFNA5;DFNA5, deafness associated tumor suppressor;Dfna5h;EG14210;Fin;Fin15;gasdermin-E;ICERE-1;inversely correlated with estrogen receptor expression 1;non-syndromic hearing impairment protein 5;non-syndromic hearing impairment protein 5 homolog;nonsyndromic hearing impairment protein
Extra Details:: Enables cardiolipin binding activity. Involved in cellular response to virus and pyroptotic inflammatory response. Acts upstream of or within inner ear auditory receptor cell differentiation. Located in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 5 and sensorineural hearing loss. Orthologous to human GSDME (gasdermin E).