A28573
GSDMD (Full Length+N terminal) Rabbit monoclonal antibody
Size
POA
- SKU:
- A28573
- Additional Names:
- 1810036L03Rik|DF5L|Dfna5l|GsdmD-1|Gsdmdc1|M2-4
- Application:
- ELISA, WB
- Molecular Weight:
- 31 kDa(N terminal)/53 kDa(Full Length)
- Species Reactivity:
- Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Mouse
- Immunogen:
- Recombinant protein (or fragment). This information is considered to be commercially sensitive.
- Uniprot:
- Q9D8T2
- Synonyms:
- 1810036L03Rik;AW558049;DF5;DF5L;Dfn;Dfna5l;FKSG10;gasdermin domain containing 1;gasdermin domain-containing protein 1;gasdermin-D;gasderminD-1;GsdmD-1;Gsdmdc;Gsdmdc1;M2-4
- Extra Details:
- Enables phospholipid binding activity; transcription coactivator activity; and wide pore channel activity. Involved in several processes, including defense response to bacterium; positive regulation of interleukin-1 beta production; and protein-containing complex assembly. Acts upstream of or within ceramide biosynthetic process; plasma membrane repair; and protein maturation. Located in cytosol; extracellular space; and mitochondrial membrane. Part of NLRP3 inflammasome complex. Is active in plasma membrane. Is expressed in several structures, including aorta; gut; liver; metanephros; and spleen. Orthologous to human GSDMD (gasdermin D).
- Shipping Conditions:
- Blue Ice