A28508
IRF1 Rabbit polyclonal antibody
Size
£152.00
- SKU:
- A28508
- Additional Names:
- Irf-1
- Application:
- ELISA, WB
- Molecular Weight:
- 46 kDa
- Species Reactivity:
- Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Mouse
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Uniprot:
- P15314
- Synonyms:
- AU020929;interferon regulatory factor 1;Irf;IRF-1;MAR
- Extra Details:
- Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including defense response to other organism; regulation of T cell activation; and regulation of gene expression. Acts upstream of or within CD8-positive, alpha-beta T cell differentiation; positive regulation of interleukin-12 production; and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in several structures, including bone marrow; early conceptus; eye; genitourinary system; and gut. Human ortholog(s) of this gene implicated in asthma; immunodeficiency 117; lung cancer (multiple); smallpox; and stomach cancer (multiple). Orthologous to human IRF1 (interferon regulatory factor 1).
- Shipping Conditions:
- Blue Ice