APC/Cyanine7 Rabbit anti-Human CD61 monoclonal antibody

Size

POA

SKU:: A28504
Additional Names:: BDPLT16|BDPLT2|BDPLT24|CD61|GP3A|GPIIIa|GT|GT2
Application:: Flow Cytometry
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Uniprot:: P05106
Synonyms:: antigen CD61;BDPLT16;BDPLT2;BDPLT24;CD61;GP3A;GPIIIa;GT;GT2;integrin beta 3;integrin beta chain, beta 3;integrin beta-3;integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61);platelet membrane glycoprotein IIIa
Extra Details:: CD61, also known as integrin beta 3 and glycoprotein IIIa (gpIIIa), is a 90 kDa type I integral transmembrane glycoprotein. As a member of the integrin family, it associates with platelet glycoprotein IIb (CD41) to form the CD41/CD61 complex (integrin A AlphaIIbB Beta3), and with integrin alpha V (CD51) to form the A AlphaVB Beta3 integrin (CD51/CD61). The CD41/CD61 complex is expressed on platelets and megakaryocytes, where it mediates platelet activation and aggregation through interactions with fibrinogen, fibronectin, von Willebrand factor (vWF), and other RGD-containing adhesion molecules. The CD51/CD61 integrin is expressed on platelets, osteoclasts, fibroblasts, macrophages, and tumor cells involved in metastasis and adenovirus infection, where it binds to RGD motifs present in extracellular matrix proteins.

Shipping Conditions:: Blue Ice