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A28482

TFEB Rabbit polyclonal antibody

Size

£152.00

SKU:
A28482
Additional Names:
bHLHe35|Tcfeb
Application:
ELISA, WB, IP
Molecular Weight:
65-70 kDa
Species Reactivity:
Mouse
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Uniprot:
Q9R210
Synonyms:
70 kDa mitochondrial autoantigen of primary biliary cirrhosis;bHLHe3;bHLHe35;dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex;dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial;DLTA;E2;E2 component of pyruvate dehydrogenase complex;M2 antigen complex 70 kDa subunit;PBC;PDC-E2;PDCE2;pyruvate dehydrogenase complex component E2;Tcfeb;transcription factor EB
Extra Details:
Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein heterodimerization activity. Involved in several processes, including defense response to Gram-negative bacterium; embryonic placenta development; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within lysosome organization. Located in cytoplasm. Part of transcription regulator complex. Colocalizes with nucleus. Is expressed in several structures, including cardiovascular system; central nervous system; early conceptus; genitourinary system; and gut gland. Orthologous to human TFEB (transcription factor EB).
Shipping Conditions:
Blue Ice