PE Rabbit anti-Mouse CD86 monoclonal antibody

Size

POA

SKU:: A28463
Additional Names:: B7|B7-2|B7.2|B70|Cd28l2|CD86|CLS1|ETC-1|Ly-58|Ly58|MB7|MB7-2|TS/A-2
Application:: Flow Cytometry
Species Reactivity:: Mouse
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Uniprot:: P42082
Synonyms:: activation B7-2 antigen;B-lymphocyte activation antigen B7-2;B7;B7-2;B7.2;B70;BU63;Cd28l;Cd28l2;CD28LG2;CD86 antigen (CD28 antigen ligand 2, B7-2 antigen);CLS1;CTLA-4 counter-receptor B7.2;early T cell costimulatory molecule-1;Early T-cell costimulatory molecule 1;ETC-1;FUN-1;LAB72;Ly-5;Ly-58;Ly5;Ly58;MB7;MB7-2;T-lymphocyte activation antigen CD86;TS/A-2
Extra Details:: Predicted to enable signaling receptor binding activity. Involved in several processes, including CD40 signaling pathway; activation of phospholipase C activity; and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including cellular response to lipopolysaccharide; defense response to virus; and positive regulation of T cell proliferation. Located in external side of plasma membrane and intracellular membrane-bounded organelle. Is expressed in central nervous system and retina. Used to study Guillain-Barre syndrome. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; autoimmune disease (multiple); chronic lymphocytic leukemia; chronic obstructive pulmonary disease; and systemic scleroderma. Orthologous to human CD86 (CD86 molecule).

Shipping Conditions:: Blue Ice