A28460
Caspase-8 Rabbit monoclonal antibody
Size
POA
- SKU:
- A28460
- Additional Names:
- CASP-8|Caspase-8|FLICE|MACH|Mch5
- Application:
- ELISA, WB, IF, ICC, IP
- Molecular Weight:
- 57 kDa(pro)/43 kDa(cleavad)
- Species Reactivity:
- Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Mouse
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Uniprot:
- O89110
- Synonyms:
- ALPS2B;apoptotic cysteine protease;apoptotic protease Mch-5;CAP4;Casp;Casp-8;caspase 8, apoptosis-related cysteine peptidase;caspase 8, apoptosis-related cysteine protease;caspase-8;FADD-homologous ICE/CED-3-like protease;FADD-like ICE;Fas-linked ICE-like protease;FLI;FLICE;ICE-like apoptotic protease 5;MAC;MACH;MACH-alpha-1/2/3 protein;MACH-beta-1/2/3/4 protein;MCH5;MORT1-associated ced-3 homolog
- Extra Details:
- This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, an initiator of apoptotic cell death, is activated by death-inducing tumor necrosis family receptors and targets downstream effectors. In mouse deficiency of this gene can cause embryonic lethality. This protein may have a role in embryogenesis. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
- Shipping Conditions:
- Blue Ice