PE Rabbit anti-Human VEGFR-3/FLT-4 monoclonal antibody

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POA

SKU:: A28354
Additional Names:: CHTD7|FLT-4|FLT41|LMPH1A|LMPHM1|PCL|VEGFR-3|VEGFR3
Application:: Flow Cytometry
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: YSMTPPTLNITEESHVIDTGDSLSISCRGQHPLEWAWPGAQEAPATGDKDSEDTGVVRDCEGTDARPYCKVLLLHEVHANDTGSYVCYYKYIKARIEGTTAASSYVFVRDFEQPFINKPDTLLVNRKDAMWVPCLVSIPGLNVTLRSQSSVLWPDGQEVVWDDRRGMLVSTPLLHDALYLQCETTWGDQDFLSNPFLVHITGNELYDIQLLPRKSLELLVGEKLVLNCTVWAEFNSGVTFDWDYPGKQAERGKWVPERRSQQTHTELSSILTIHNVSQHDLGSYVCKANNGIQRFRESTEVIVHENPFISVEWLKGPILEATAGDELVKLPVKLAAYPPPEFQWYKDGKALSGRHSPHALVLKEVTEASTGTYTLALWNSAAGLRRNISLELVVNVPPQIHEKEASSPSIYSRHSRQALTCTAYGVPLPLSIQWHWRPWTPCKMFAQRSLRRRQQQDLMPQCRDWRAVTTQDAVNPIESLDTWTEFVEGKNKTVSKLVIQNANVSAMYKCVVSNKVGQDERLIYFYVTTIPDGFTIESKPSEELLEGQPVLLSCQADSYKYEHLRWYRLNLSTLHDAHGNPLLLDCKNVHLFATPLAASLEEVAPGARHATLSLSIPRVAPEHEGHYVCEVQDRRSHDKHCHKKYLSVQALEAPRLTQNLTDLLVNVSDSLEMQCLVAGAHAPSIVWYKDERLLEEKSGVDLADSNQKLSIQRVREEDAGRYLCSVCNAKGCVNSSASVAVEGSEDKGSMEI
Uniprot:: P35916
Synonyms:: CHTD7;Feline McDonough Sarcoma (FMS)-like tyrosine kinase 4;FLT-4;FLT41;fms related tyrosine kinase 4;fms-like tyrosine kinase 4;LMPH1A;LMPHM1;PCL;primary congenital lymphedema;tyrosine-protein kinase receptor FLT4;vascular endothelial growth factor receptor 3;VEGF receptor-3;VEGFR-3;VEGFR3
Extra Details:: Vascular Endothelial Growth Factor Receptor 3 (VEGFR3) is a 195 kDa transmembrane receptor tyrosine kinase. The VEGF receptor features seven extracellular immunoglobulin-like (Ig) domains, a single transmembrane domain, and a conserved intracellular tyrosine kinase domain. In adults, VEGFR3 expression is primarily restricted to lymphatic endothelial cells and is known to govern lymphangiogenesis. The binding of VEGF-C or VEGF-D to VEGFR3 induces trans-phosphorylation of tyrosine residues within its intracellular domain. This phosphorylation event facilitates the recruitment of downstream signaling molecules, ultimately leading to the activation of the ERK1/2 and Akt signaling cascades.

Shipping Conditions:: Blue Ice