A28294
RAB7 Mouse monoclonal antibody
Size
POA
- SKU:
- A28294
- Additional Names:
- CMT2B|PRO2706|RAB7
- Application:
- ELISA, WB, IHC-P, IF, ICC
- Molecular Weight:
- 23 kda
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Mouse
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- IQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKASAESCSC
- Uniprot:
- P51149
- Synonyms:
- CMT2B;PRO2706;RAB7;RAB7, member RAS oncogene family;Ras-associated protein RAB7;ras-related protein Rab-7a
- Extra Details:
- RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
- Shipping Conditions:
- Blue Ice