PDE3A Rabbit polyclonal antibody

Size

£152.00

SKU:: A28279
Additional Names:: CGI-PDE|CGI-PDE A|CGI-PDE-A|HTNB
Application:: ELISA, WB, IP
Molecular Weight:: 125 kDa
Species Reactivity:: Mouse
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Uniprot:: Q9Z0X4
Synonyms:: A930022O17Rik;C87899;cAMP phosphodiesterase, myocardial cGMP-inhibited;CGI-PDE;CGI-PDE A;CGI-PDE-A;cGMP-inhibited 3',5'-cyclic phosphodiesterase A;cGMP-inhibited phosphodiesterase;cyclic GMP-inhibited phosphodiesterase A;HTNB;phosphodiesterase 3A, cGMP-inhibited
Extra Details:: This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.