ABflo[R] 647 Rabbit anti-Mouse CD223/LAG-3 monoclonal antibody

Size

POA

SKU:: A28268
Additional Names:: CD223|LAG-3|Ly66
Application:: Flow Cytometry
Molecular Weight:: Refer to figures
Species Reactivity:: Mouse
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: GPGKELPVVWAQEGAPVHLPCSLKSPNLDPNFLRRGGVIWQHQPDSGQPTPIPALDLHQGMPSPRQPAPGRYTVLSVAPGGLRSGRQPLHPHVQLEERGLQRGDFSLWLRPALRTDAGEYHATVRLPNRALSCSLRLRVGQASMIASPSGVLKLSDWVLLNCSFSRPDRPVSVHWFQGQNRVPVYNSPRHFLAETFLLLPQVSPLDSGTWGCVLTYRDGFNVSITYNLKVLGLEPVAPLTVYAAEGSRVELPCHLPPGVGTPSLLIAKWTPPGGGPELPVAGKSGNFTLHLEAVGLAQAGTYTCSIHLQGQQLNATVTLAVITVTPKSFGLPGSRGKLLCEVTPASGKERFVWRPLNNLSRSCPGPVLEIQEARLLAERWQCQLYEGQRLLGATVYAAESSSGAHSARRISGDLKGGHL
Uniprot:: Q61790
Synonyms:: activation-induced cytidine deaminase-linked autoimmunity protein;aida;CD223;LAG;LAG-3;Ly6;Ly66;lymphocyte activation gene 3 protein;lymphocyte-activation gene 3
Extra Details:: Enables MHC class II protein binding activity and transmembrane signaling receptor activity. Involved in negative regulation of regulatory T cell differentiation; plasmacytoid dendritic cell activation; and regulation of immune response. Acts upstream of or within cell surface receptor signaling pathway; negative regulation of interleukin-2 production; and positive regulation of natural killer cell mediated cytotoxicity. Located in external side of plasma membrane and extracellular region. Orthologous to human LAG3 (lymphocyte activating 3).

Shipping Conditions:: Blue Ice