APC Mouse anti-Human Annexin A1 monoclonal antibody

Size

POA

SKU:: A28227
Additional Names:: ANX1|LPC1
Application:: Flow Cytometry
Molecular Weight:: Refer to figures
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Mouse
Reactivities:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Uniprot:: P04083
Synonyms:: annexin A1;Annexin I;annexin I (lipocortin I);annexin-1;ANX1;calpactin II;calpactin-2;chromobindin-9;epididymis secretory sperm binding protein;Lipocortin I;LPC1;p35;phospholipase A2 inhibitory protein
Extra Details:: Annexin A1 (also known as lipocortin-1) is a membrane-localized protein capable of binding phospholipids. It functions as an inhibitor of phospholipase A2 (PLA2) and exhibits potent anti-inflammatory activity. Loss of function or aberrant expression of this gene has been detected in a variety of tumors. Phospholipase A2 is essential for the biosynthesis of potent inflammatory mediators, namely prostaglandins and leukotrienes. By virtue of its PLA2 inhibitory activity, lipocortin-1 acts as a key anti-inflammatory protein.