A28220
Biotin Rabbit anti-Mouse CD45 monoclonal antibody
Size
POA
- SKU:
- A28220
- Additional Names:
- B220|Cd45|CD45R|L-CA|loc|Ly-5|Lyt-4|T200
- Application:
- Flow Cytometry
- Species Reactivity:
- Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Mouse
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Uniprot:
- P06800
- Synonyms:
- B220;CD45;CD45 antigen;CD45R;GP180;L-CA;LCA;leukocyte common antigen;loc;Ly-;Ly-5;LY5;lymphocyte antigen 5;lymphocyte common antigen;Lyt-;Lyt-4;protein tyrosine phosphatase, receptor type, c polypeptide;receptor-type tyrosine-protein phosphatase C;T200;T200 glycoprotein;T200 leukocyte common antigen
- Extra Details:
- CD45 is a 180-240 kD glycoprotein, also known as the leukocyte common antigen (LCA), T200, or Ly-5. As a member of the protein tyrosine phosphatase (PTP) family, it is expressed on all hematopoietic cells except mature erythrocytes and platelets. Different isoforms of CD45 are generated through the alternative splicing of exons 4, 5, and 6, which encode the A, B, and C determinant regions, respectively. CD45 plays a critical role in the signal transduction of both the T-cell receptor (TCR) and B-cell receptor (BCR). These isoforms exhibit high specificity for the cell's activation and maturation status, as well as the cell type. Key ligands for CD45 include galectin-1, CD2, CD3, TCR, CD4, CD22, and Thy-1.
- Shipping Conditions:
- Blue Ice