A28207
Caspase-1 Rabbit monoclonal antibody
Size
POA
- SKU:
- A28207
- Additional Names:
- ICE|Il1bc
- Application:
- ELISA, WB
- Molecular Weight:
- 20 kDa/35 kDa/48 kDa
- Species Reactivity:
- Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Mouse
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Uniprot:
- P29452
- Synonyms:
- Casp;CASP-1;CASP1 nirs variant 1;caspase 1, apoptosis-related cysteine peptidase;caspase-1;caspase-1 isoform alpha;IC;ICE;IL-1 beta-converting enzyme;IL-1B converting enzyme;IL-1BC;Il1;IL1B-convertase;IL1BC;interleukin 1-B converting enzyme;interleukin 1, beta, convertase;interleukin-1 beta convertase;interleukin-1 beta-converting enzyme;P45
- Extra Details:
- Enables cysteine-type endopeptidase activity. Involved in several processes, including AIM2 inflammasome complex assembly; positive regulation of canonical NF-kappaB signal transduction; and positive regulation of interleukin-1 beta production. Acts upstream of or within several processes, including membrane hyperpolarization; mitochondrial depolarization; and positive regulation of cytokine production. Located in extracellular region. Part of IPAF inflammasome complex. Is active in cytosol. Is expressed in several structures, including forelimb mesenchyme; knee joint; oocyte; small intestine; and telencephalon. Orthologous to human CASP1 (caspase 1).
- Shipping Conditions:
- Blue Ice