Biotin Rabbit anti-Mouse CD49b/ITGA2 monoclonal antibody

Size

POA

SKU:: A28151
Additional Names:: CD49B|DX5|GPIa
Application:: Flow Cytometry
Species Reactivity:: Mouse
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: SLVDVVVVCDESNSIYPWEAVKNFLVKFVTGLDIGPKKTQVALIQYANEPRIIFNLNDFETKEDMVQATSETRQHGGDLTNTFRAIEFARDYAYSQTSGGRPGATKVMVVVTDGESHDGSKLKTVIQQCNDDEILRFGIAVLGYLNRNALDTKNLIKEIKAIASTPTERYFFNVADEAALLEKAGTLGEQIFSIEGTVQ
Uniprot:: Q62469
Synonyms:: alpha 2 subunit of VLA-2 receptor;BR;CD49 antigen-like family member B;CD49B;collagen receptor;DX5;GPIa;HPA-5;human platelet alloantigen system 5;integrin alpha-2;integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor);platelet antigen Br;platelet glycoprotein GPIa;platelet membrane glycoprotein Ia;very late activation protein 2 receptor, alpha-2 subunit;VLA-2;VLA-2 receptor, alpha 2 subunit;VLA-2 subunit alpha;VLAA2
Extra Details:: Enables amyloid-beta binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; positive regulation of cell migration; and positive regulation of cellular component organization. Predicted to act upstream of or within cell adhesion. Located in basal part of cell and external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; eye; and genitourinary system. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; artery disease (multiple); blood platelet disease (multiple); diabetes mellitus (multiple); and von Willebrand's disease (multiple). Orthologous to human ITGA2 (integrin subunit alpha 2).

Shipping Conditions:: Blue Ice