PE Rabbit anti-Human CD366/TIM-3/HAVCR2 monoclonal antibody

Size

POA

SKU:: A27986
Additional Names:: CD366|HAVcr-2|KIM-3|SPTCL|Tim-3|TIM3|TIMD-3|TIMD3
Application:: Flow Cytometry
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: SEVEYRAEVGQNAYLPCFYTPAAPGNLVPVCWGKGACPVFECGNVVLRTDERDVNYWTSRYWLNGDFRKGDVSLTIENVTLADSGIYCCRIQIPGIMNDEKFNLKLVIKPAKVTPAPTRQRDFTAAFPRMLTTRGHGPAETQTLGSLPDINLTQISTLANELRDSRLANDLRDSGATIR
Uniprot:: Q8TDQ0
Synonyms:: CD366;HAVcr-2;hepatitis A virus cellular receptor 2;kidney injury molecule-3;KIM-3;SPTCL;T cell immunoglobulin mucin 3;T-cell immunoglobulin and mucin domain-containing protein 3;T-cell immunoglobulin mucin family member 3;T-cell immunoglobulin mucin receptor 3;T-cell membrane protein 3;Tim-3;TIM3;TIMD-3;TIMD3
Extra Details:: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Shipping Conditions:: Blue Ice