ABflo[R] 488 Rabbit anti-Human Cytokeratin 18/KRT18 monoclonal antibody

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£417.00

Was £556.00

SKU:: A27943
Additional Names:: CK-18|CYK18|K18
Application:: Flow Cytometry
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: KSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIVDGKVVSETNDTKVLRH
Uniprot:: P05783
Synonyms:: cell proliferation-inducing gene 46 protein;CK-18;CYK18;cytokeratin 18;Cytokeratin-18;K18;keratin 18, type I;Keratin-18;keratin, type I cytoskeletal 18
Extra Details:: Keratins (also known as cytokeratins) are intermediate filament proteins primarily expressed in epithelial cells. A keratin heterodimer, composed of one acidic keratin (or type I keratin, keratins 9 to 23) and one basic/neutral keratin (or type II keratin, keratins 1 to 8), polymerizes to form filaments. The tissue-specific and differentiation-specific expression patterns of keratin isoforms enable them to serve as valuable biomarkers. Studies have confirmed that mutations in keratin genes are associated with dermatological disorders, liver and pancreatic diseases, and inflammatory bowel diseases.