APC Rabbit anti-Mouse H-2Kd/H-2Dd monoclonal antibody

Size

POA

SKU:: A27735
Additional Names:: H2-D1, H-2D|H2-K1, H-2K, H2-K
Application:: Flow Cytometry
Species Reactivity:: Mouse
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: SHSLRYFVTAVSRPGFGEPRYMEVGYVDNTEFVRFDSDAENPRYEPRARWIEQEGPEYWERETRRAKGNEQSFRVDLRTALRYYNQSAGGSHTLQWMAGCDVESDGRLLRGYWQFAYDGCDYIALNEDLKTWTAADMAAQITRRKWEQAGAAERDRAYLEGECVEWLRRYLKNGNATLLRTDPPKAHVTHHRRPEGDVTLRCWALGFYPADITLTWQLNGEELTQEMELVETRPAGDGTFQKWASVVVPLGKEQKYTCHVEHEGLPEPLTLRWGKE
Uniprot:: P01900, P01902
Synonyms:: class I major histocompatibility antigen H-2Kd;H-2 class I histocompatibility antigen, D-B alpha chain;H-2 class I histocompatibility antigen, K-B alpha chain;H-2 class I histocompatibility antigen, K-D alpha chain;H-2 class I histocompatibility antigen, K-K alpha chain;H-2 class I histocompatibility antigen, K-Q alpha chain;H-2 class I histocompatibility antigen, K-W28 alpha chain;H-2D;H-2D cell surface glycoprotein;H-2K;H-2K(B);H-2K(d);H-2K(K);H-2K(Q);H2-D;H2-D1;H2-DC1-beta transplantation antigen protein;H2-K;H2-K_p;H2-K1;histocompatibility 2, K region, promoter 1;K-f;MHC class I antigen;MHC class I H-2Dp;MHC class I H2 antigen;MHC class I H2-K-b-alpha-2 cell surface glycoprotein;MHC class I heavy chain H2-K;MHC class I heavy chain heavy chain;MHC class I heavy chain maturation peptide;MHC class II antigen D;MHC class II antigen K;MHC H2-D-q alpha-chain;MHC H2-K transplantation antigen;Q5k protein
Extra Details:: H-2Kd and H-2Dd are classical MHC class I alloantigens encoded within the murine major histocompatibility complex (H-2 system). These transmembrane glycoproteins function as critical components of the adaptive immune system by mediating antigen presentation to cytotoxic T lymphocytes (CTLs) through interactions with the CD3/T-cell receptor (TCR) complex and the CD8 co-receptor. Structurally, these MHC I molecules consist of a polymorphic heavy A Alpha-chain non-covalently associated with the invariant light chain B Beta2-microglobulin (B Beta2m), forming a peptide-binding groove that accommodates 8-10 amino acid antigenic peptides derived from endogenous protein degradation via the proteasomal pathway.

Shipping Conditions:: Blue Ice