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A2750

IGF2BP3 Rabbit polyclonal antibody

Size

£152.00

SKU:
A2750
Additional Names:
CT98|IGF2BP3|IMP-3|IMP3|KOC|KOC1|VICKZ3
Application:
ELISA, WB
Molecular Weight:
72kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGKIELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETAVVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRL
Uniprot:
O00425
Synonyms:
cancer/testis antigen 98;CT98;IGF-II mRNA-binding protein 3;IGF2 mRNA-binding protein 3;IMP-3;IMP3;insulin-like growth factor 2 mRNA-binding protein 3;KH domain containing protein overexpressed in cancer;KH domain-containing protein overexpressed in cancer;KOC;KOC1;VICKZ family member 3;VICKZ3
Extra Details:
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.
Shipping Conditions:
Blue Ice