UCP1 Rabbit monoclonal antibody

Size

POA

SKU:: A27158
Additional Names:: Slc25a7|Ucp
Application:: ELISA, WB, IHC-P, IP
Molecular Weight:: 33 kDa
Species Reactivity:: Mouse
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Uniprot:: P12242
Synonyms:: AI385626;mitochondrial brown fat uncoupling protein 1;Slc2;SLC25A7;solute carrier family 25 member 7;thermogenin;UCP;UCP 1;uncoupling protein 1 (mitochondrial, proton carrier);uncoupling protein 1, mitochondrial;uncoupling protein, mitochondrial
Extra Details:: Enables long-chain fatty acid binding activity; oxidative phosphorylation uncoupler activity; and purine ribonucleotide binding activity. Involved in several processes, including cellular response to cold; diet induced thermogenesis; and positive regulation of cold-induced thermogenesis. Acts upstream of or within brown fat cell differentiation and regulation of transcription by RNA polymerase II. Located in mitochondrial inner membrane. Is expressed in several structures, including adipose tissue; adrenal gland; submandibular gland; testis; and thymus. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Orthologous to human UCP1 (uncoupling protein 1).