Olig2 Rabbit monoclonal antibody

Size

POA

SKU:: A26746
Additional Names:: BHLHB1|bHLHe19|OLIGO2|PRKCBP2|RACK17
Application:: ELISA, WB, IHC-P, IF
Molecular Weight:: 35 kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Uniprot:: Q13516
Synonyms:: basic domain, helix-loop-helix protein, class B, 1;BHLHB1;bHLHe19;class B basic helix-loop-helix protein 1;class E basic helix-loop-helix protein 19;human protein kinase C-binding protein RACK17;OLIGO2;oligodendrocyte lineage transcription factor 2;oligodendrocyte transcription factor 2;oligodendrocyte-specific bHLH transcription factor 2;PRKCBP2;protein kinase C-binding protein 2;Protein kinase C-binding protein RACK17;RACK17
Extra Details:: This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.