A2586
DRP1 Rabbit polyclonal antibody
Size
£152.00
- SKU:
- A2586
- Additional Names:
- DLP1|DRP1|DVLP|DYMPLE|EMPF|EMPF1|HDYNIV|OPA5
- Application:
- ELISA, WB, IHC-P, IF, ICC
- Molecular Weight:
- 78kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- VSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKLIQDSRRETKNVASGGGGVGDGVQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW
- Uniprot:
- O00429
- Synonyms:
- DLP1;Dnm1p/Vps1p-like protein;DRP1;DVLP;DYMPLE;dynamin family member proline-rich carboxyl-terminal domain less;dynamin-1-like protein;Dynamin-like protein;dynamin-like protein 4;dynamin-like protein IV;dynamin-related protein 1;EMPF;EMPF1;HDYNIV;OPA5
- Extra Details:
- This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.
- Shipping Conditions:
- Blue Ice