A25847
CYP8B1 Rabbit polyclonal antibody
Size
POA
- SKU:
- A25847
- Additional Names:
- CP8B|CYP12
- Application:
- ELISA, WB, IF
- Molecular Weight:
- 58kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Uniprot:
- Q9UNU6
- Synonyms:
- 7 alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase;7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase;7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase;CP8B;CYP12;CYPVIIIB1;cytochrome P450 8B1;cytochrome P450, family 8, subfamily B, polypeptide 1;cytochrome P450, subfamily VIIIB (sterol 12-alpha-hydroxylase), polypeptide 1;sterol 12-alpha-hydroxylase
- Extra Details:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless.
- Shipping Conditions:
- Blue Ice