A25439
COL1A1 Rabbit polyclonal antibody
Size
£152.00
- SKU:
- A25439
- Additional Names:
- CAFYD|Collagen I/COL1A1|EDSARTH1|EDSC|OI1|OI2|OI3|OI4
- Application:
- ELISA, WB, IF, ICC
- Molecular Weight:
- 220kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- STEASQNITYHCKNSVAYMDQQTGNLKKALLLQGSNEIEIRAEGNSRFTYSVTVDGCTSHTGAWGKTVIEYKTTKTSRLPIIDVAPLDVGAPDQEFGFDVGPVCFL
- Uniprot:
- P02452
- Synonyms:
- alpha-1 type I collagen;alpha1(I) procollagen;CAFYD;collagen alpha 1 chain type I;collagen alpha-1(I) chain;collagen alpha-1(I) chain preproprotein;collagen of skin, tendon and bone, alpha-1 chain;collagen, type I, alpha 1;EDSARTH1;EDSC;OI1;OI2;OI3;OI4;pro-alpha-1 collagen type 1;type I proalpha 1;type I procollagen alpha 1 chain
- Extra Details:
- This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
- Shipping Conditions:
- Blue Ice