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A25426

SRGN Rabbit polyclonal antibody

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£152.00

SKU:
A25426
Additional Names:
PPG|PRG|PRG1
Application:
ELISA, WB, IF
Molecular Weight:
24kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
LLPGESNKIPRLRTDLFPKTRIQDLNRIFPLSEDYSGSGFGSGSGSGSGSGSGFLTEMEQDYQLVDESDAFHDNLRSLDRNLPSDSQDLGQHGLEEDFML
Uniprot:
P10124
Synonyms:
hematopoetic proteoglycan core peptide;hematopoetic proteoglycan core protein;hematopoietic proteoglycan core protein;p.PG;platelet proteoglycan core protein;PPG;PRG;PRG1;proteoglycan 1, secretory granule;proteoglycan protein core for mast cell secretory granule;secretory granule proteoglycan core peptide;secretory granule proteoglycan core protein;serglycin;serglycin proteoglycan
Extra Details:
This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene.
Shipping Conditions:
Blue Ice