ABflo[R] 488 Rabbit anti-Human MICA/MICB monoclonal antibody

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POA

SKU:: A25276
Additional Names:: MIC-A|MICB|PERB11.1|PERB11.2
Application:: Flow Cytometry
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: AEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSG
Uniprot:: Q29980, Q29983
Synonyms:: HLA class I antigen;major histocompatibility complex class I chain-related protein A;MHC class I antigen-related protein B;MHC class I chain-related protein A;MHC class I chain-related protein B;MHC class I mic-B antigen;MHC class I polypeptide-related sequence A;MHC class I polypeptide-related sequence B;MHC class I related chain A;MHC class I related sequence A;MHC class I-like molecule PERB11.2-IMX;MIC-A;PERB11.1;PERB11.2;stress inducible class I homolog;truncated MHC class I polypeptide-related sequence A;truncated MICA
Extra Details:: This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

Shipping Conditions:: Blue Ice